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Prof. Dr. med.
Antonios Douros

(he/ him)

antonios.douros@charite.de

Associate Professor of Pharmacoepidemiology
Institute of Clinical Pharmacology and Toxicology
Charité – Universitätsmedizin Berlin


       
Charité Berlin    DFG

Welcome

 

I am an Associate Professor at the Institute of Clinical Pharmacology and Toxicology at Charité in Berlin and Head of the Douros Lab. The research in our lab focuses on the effectiveness and safety of medications in vulnerable populations, including patients with chronic liver disease, older adults, patients subjected to polypharmacy and at risk of drug-drug interactions, and patients with a genetic susceptibility to drug toxicity. Given the underrepresentation of such populations in randomized trials, our lab aims to provide much needed evidence on the benefit-risk profile of drugs.

For the implementation of our research program, we conduct both hypothesis-generating and hypothesis-testing studies. To this end, we use multiple data sources including spontaneous reports from the FDA Adverse Event Reporting System, German and Canadian administrative healthcare data, electronic medical records from the UK, and the UK Biobank. We also collaborate with several experts in the area of real-world evidence in Canada, Germany, and Greece. The research in our lab is supported by the German Research Foundation.

Interests

  • Pharmacoepidemiology
  • Pharmacovigilance
  • Clinical Pharmacology
  • Drug-drug interactions
  • Vulnerable populations

Education

  • Postdoc in Pharmacoepidemiology, McGill University
  • Doctorate Degree (Dr. med.), Charité – Universitätsmedizin Berlin
  • Medical Degree, Charité – Universitätsmedizin Berlin

Experience

  • 2024 – present  Deputy Head
    Institute of Clinical Pharmacology and Toxicology, Charité – Universitätsmedizin Berlin
  • 2023 – present  Associate Professor (Heisenberg)
    Institute of Clinical Pharmacology and Toxicology, Charité – Universitätsmedizin Berlin
  • 2023 – present  Adjunct Professor
    Department of Epidemiology, Biostatistics, and Occupational Health, McGill University
  • 2023 – present  Adjunct Professor
    School of Epidemiology and Public Health, University of Ottawa
  • 2019 – 2023  Assistant Professor
    Department of Medicine (Division Clinical Epidemiology), McGill University
  • 2019 – 2023  Investigator
    Centre for Clinical Epidemiology (Pharmacoepidemiology Research Unit), Lady Davis Institute for Medical Research
  • 2019 – 2023  Associate Member
    Department of Epidemiology, Biostatistics, and Occupational Health, McGill University
  • 2016 – 2018  Postdoctoral Research Fellow
    Centre for Clinical Epidemiology (Pharmacoepidemiology Research Unit), Lady Davis Institute for Medical Research
  • 2014 – 2015  Research Fellow
    Department of Clinical Epidemiology, Leibniz Institute for Prevention Research and Epidemiology – BIPS
  • 2012 – 2016  Clinical Pharmacology Resident
    Institute of Clinical Pharmacology and Toxicology, Charité – Universitätsmedizin Berlin
  • 2009 – 2011  Neurology Resident
    Department of Early Neurological Rehabilitation & Intensive Care Unit, Medical Park Berlin Humboldtmühle

Selected Talks

  • Aug 30, 2026 · When an active comparator is not available: prevalent new-user design as a potential solution
    42. Annual Meeting; International Society for Pharmacoepidemiology
    Milan, IT
  • May 30, 2026 · Emulating randomized trials using real-world data
    35. European Meeting on Hypertension and Cardiovascular Protection, European Society of Hypertension
    Gdansk, PL
  • Sep 6, 2025 · Hepatic effect of antihypertensive drugs
    Hypertension – A Common Link Between Cardiovascular, Kidney, and Metabolic Syndrome Symposium
    Warsaw, PL
  • Apr 15, 2024 · Break on through to the other side: from pharmacology to RWE
    Mid-Year Meeting, International Society for Pharmacoepidemiology
    Orlando, FL
  • Sep 12, 2023 · Assessing the clinical effects of drug-drug interactions using cohort designs
    Therapeutics Research and Infectious Disease Epidemiology, Department of Population Medicine
    Harvard Medical School, Boston, MA

Publications

Check out my complete list of publications on PubMed.

To date, my research has resulted in >100 peer-reviewed publications. Several of them have appeared in top- and higher-tier journals including the British Medical Journal (4x), Annals of Internal Medicine, European Heart Journal, Journal of the American College of Cardiology, Diabetes Care (7x), Alzheimer’s & Dementia, JACC: Heart Failure, JAMA Network Open (2x), Neurology, Hypertension, and BMC Medicine. Moreover, my publications have been the subject of 11 editorials.

Grants, Awards & Distinctions

Research Grants as PI

  • 2026-2029 Individual Research Grant,
    German Research Foundation
    Closing important knowledge gaps in antihypertensive treatment with real-world evidence
  • 2019-2023 Project Grant,
    Canadian Institutes of Health Research
    Effectiveness and safety of direct oral anticoagulants in patients with non-valvular atrial fibrillation and liver disease
  • 2019-2022 Project Grant,
    Canadian Institutes of Health Research
    Concomitant use of sulfonylureas with warfarin and the risk of severe hypoglycemia in patients with type 2 diabetes

Personal Salary Awards

  • 2023-2028 Heisenberg Program,
    German Research Foundation
    Effectiveness and safety of medications in vulnerable populations
  • 2020-2023 Chercheur Boursier Junior 1,
    Fonds de recherche du Québec – Santé
    Efficacité et innocuité des médicaments dans les populations vulnérables
  • 2016-2018 Research Fellowship,
    German Research Foundation
    Comparative effectiveness and safety of non-vitamin K antagonist oral anticoagulants in stroke prevention in atrial fibrillation

Other Personal Awards

  • 2025 BJCP Editors’ Performance Award
    British Pharmacological Society
  • 2022 Excellence in Teaching Epidemiology
    Epidemiology, Biostatistics and Occupational Health Student Society, McGill Department of Epidemiology, Biostatistics and Occupational Health
  • 2022 Travel Grant
    European Renal Association
  • 2021 Comparative Effectiveness Research Special Interest Group Spotlight Poster Award
    International Society for Pharmacoepidemiology
  • 2018 Second Best Abstract by a Student/ Postdoc
    International Society for Pharmacoepidemiology

Distinctions

  • 2024 Appointment as Associate Member
    Arzneimittelkommission der deutschen Ärzteschaft
  • 2023 Appointment as Full Member
    Canadian Institutes of Health Research College of Reviewers
  • 2022 Appointment as Associate Member
    Canadian Institutes of Health Research College of Reviewers
  • 2026 Paper Spotlight
    Charité-Universitätsmedizin Berlin, May 2026
  • 2025 Paper of the Month
    Lady Davis Institute for Medical Research, Dec 2025
  • 2023 Paper of the Month
    Lady Davis Institute for Medical Research, Apr 2023
  • 2019 Paper of the Month
    Lady Davis Institute for Medical Research, Jul 2019
  • 2019 Paper of the Quarter
    Charité Institute of Biometry and Clinical Epidemiology, Apr 2019
  • 2018 Paper of the Month
    Lady Davis Institute for Medical Research, Jul 2018
  • 2022 Best Reviewer Annals of Internal Medicine
  • 2019 Best Reviewer Annals of Internal Medicine
  • 2019 Best Reviewer Pharmacoepidemiology and Drug Safety
  • 2018 Best Reviewer Pharmacoepidemiology and Drug Safety
  • 2017 Outstanding Reviewer Cancer Epidemiology
  • 2015 Best Reviewer Pharmacoepidemiology and Drug Safety